ZenBio Scientific Publications

ZenBio supports and supplies researchers nationally and internationally with primary cells, reagents and kits to help carry out vital research in fields such as obesity and diabetes. Here are a selected group of manuscripts both from ZenBio scientists and researchers world-wide who have utilized our products.

Subcutaneous Preadipocyte and Adipocyte Media Publications

FGF-21 as a novel metabolic regulator

Alexei Kharitonenkov, Tatiyana L. Shiyanova, Anja Koester, Amy M. Ford, Radmila Micanovic, Elizabeth J. Galbreath, George E. Sandusky, Lisa J. Hammond, Julie S. Moyers, Rebecca A. Owens, Jesper Gromada, Joseph T. Brozinick, Eric D. Hawkins, Victor J. Wroblewski, De-Shan Li, Farrokh Mehrbod, S. Richard Jaskunas, and Armen B. Shanafelt J. Clin. Invest., Jun 2005; 115: 1627 - 1635.

Human Keratinocytes Publications: Skeletal Myoblasts

A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling

Michael J. Bollong, Gihoon Lee, John S. Coukos, Hwayoung Yun, Claudio Zambaldo, Jae Won Chang, Emily N. Chin, Insha Ahmad, Arnab K. Chatterjee, Luke L. Lairson, Peter G. Schultz & Raymond E. Moellering https://doi.org/10.1038/s41586-018-0622-0

Animal Serum Publications: Preadipocytes

Flash Frozen, Fresh & Formalin Fixed Tissue Samples Publications

The genetic regulatory signature of type 2 diabetes in human skeletal muscle

Laura J. Scott, Michael R. Erdos, Jeroen R. Huyghe, Ryan P. Welch, Andrew T. Beck, Brooke N. Wolford, Peter S. Chines, John P. Didion, arisu Narisu, Heather M. Stringham, D. Leland Taylor, Anne U. Jackson, Swarooparani Vadlamudi, Lori L. Bonnycastle, Leena Kinnunen, Jouko Saramies, Jouko Sundvall, Ricardo D'Oliveira Albanus, Anna Kiseleva, John Hensley
Nature Communications 7, Article number: 11764 doi:10.1038/ncomms11764

Tissue-specific alternative splicing of TCF7L2

L. Prokunina-Olsson, C. Welch, O. Hansson, N. Adhikari, L. J. Scott, N. Usher, M. Tong, A. Sprau, A. Swift, L. L. Bonnycastle, M. R. Erdos, Z. He, R. Saxena, B. Harmon, O. Kotova, E. P. Hoffman, D. Altshuler, L. Groop, M. Boehnke, F. S. Collins and J. L. Hall Hum Mol Genet. 2009; 18 (20): 3795-804.

Subcutaneous Preadipocytes and Adipocytes

Adipose tissue mass is modulated by SLUG (SNAI2)

Pedro Antonio Pérez-Mancera, Camino Bermejo-Rodríguez, Inés Gonzaález-Herrero, Michel Herranz, Teresa Flores, Rafael Jiménez, and Isidro Sánchez-García Hum. Mol. Genet., Dec 2007; 16: 2972 - 2986.

Nicotinic Acid Receptor Agonists Differentially Activate Downstream Effectors.

Jeremy G. Richman, Martha Kanemitsu-Parks, Ibragim Gaidarov, Jill S. Cameron, Peter Griffin, Hong Zheng, Nuvia C. Guerra, Linda Cham, Dominique Maciejewski-Lenoir, Dominic P. Behan, Doug Boatman, Ruoping Chen, Philip Skinner, Pricilla Ornelas, M. Gerard Waters, Samuel D. Wright, Graeme Semple, and Daniel T. Connolly J. Biol. Chem., Jun 2007; 282: 18028 - 18036.

Molecular Identification of High and Low Affinity Receptors for Nicotinic Acid.

Alan Wise, Steven M. Foord, Neil J. Fraser, Ashley A. Barnes, Nabil Elshourbagy, Michelle Eilert, Diane M. Ignar, Paul R. Murdock, Klaudia Steplewski, Andrew Green, Andrew J. Brown, Simon J. Dowell, Philip G. Szekeres, David G. Hassall, Fiona H. Marshall, Shelagh Wilson, and Nicholas B. Pike J. Biol. Chem., Mar 2003; 278: 9869 - 9874.

Preadipocytes Publications

Peripheral Blood Mononuclear Cells (PBMCs) Publications

Functional Studies of Missense TREM2 Mutations in Human Stem Cell-Derived Microglia

Philip W. Brownjohn, James Smith, Ravi Solanki, Ebba Lohmann, Henry Houlden, John Hardy, Sabine Dietmann, and Frederick J. Livesey
DOI: https://doi.org/10.1016/j.stemcr.2018.03.003

Repositioning Potential of PAK4 to Osteoclastic Bone Resorption†

Sik-Won Choi1,‡, Jeong-Tae Yeon2,‡, Byung Jun Ryu1, Kwang-Jin Kim2, Seong-Hee Moon1, Hyuk Lee3, Myeung Su Lee4, Sam Youn Lee5, Jin-Chul Heo6, Sang-Joon Park7 andSeong Hwan Kim1,* DOI: 10.1002/jbmr.2468

Human Mesothelial Cells Publications

Obesity Contributes to Ovarian Cancer Metastatic Success through Increased Lipogenesis, Enhanced Vascularity, and Decreased Infiltration of M1 Macrophages

Yueying Liu1,2, Matthew N. Metzinger2, Kyle A. Lewellen1,2, Stephanie N. Cripps3, Kyle D. Carey2, Elizabeth I. Harper4, Zonggao Shi1,2, Laura Tarwater2, Annie Grisoli2,5, Eric Lee2, Ania Slusarz6,7, Jing Yang1,2, Elizabeth A. Loughran1,2, Kaitlyn Conley1,2, Jeff J. Johnson1,2, Yuliya Klymenko2,5, Lana Bruney2,7, Zhong Liang1,2, Norman J. Dovichi1,2, Bentley Cheatham8, W. Matthew Leevy2,5, and M. Sharon Stack1,2,*
doi: 10.1158/0008-5472.CAN-15-0706

3T3-L1 Publications

Insulin resistance uncoupled from dyslipidemia due to C-terminal PIK3R1 mutations

Isabel Huang-Doran, Patsy Tomlinson, Felicity Payne, Alexandra Gast, Alison Sleigh, William Bottomley,Julie Harris, Allan Daly, Nuno Rocha, Simon Rudge, Jonathan Clark, Albert Kwok, Stefano Romeo, Emma McCann, Barbara Müksch, Mehul Dattani, Stefano Zucchini, Michael Wakelam, Lazaros C. Foukas, David B. Savage, Rinki Murphy, Stephen O'Rahilly, Inês Barroso, and Robert K. Semple
JCI Insight. 2016 Oct 20; 1(17): e88766.

Human Blood Products Publications

Long-term deep-supercooling of large-volume water and red cell suspensions via surface sealing with immiscible liquids Haishui Huang, Martin L. Yarmush & O. Berk Usta
Nature Communicationsvolume 9, Article number: 3201 (2018)

A magnetic micropore chip for rapid (< 1 hour) unbiased circulating tumor cell isolation and in-situ RNA analysis

Jina Ko, Neha Bhagwat, Stephanie S. Yee, Taylor Black, Colleen Redlinger, Janae Romeo, Mark O'Hara, Arjun Raj, Erica L. Carpenter, Ben Z. Stanger and David Issadore
DOI:10.1039/C7LC00703E

Resistance to type 1 interferons is a major determinant of HIV-1 transmission fitness

Shilpa S. Iyera,b, Frederic Bibollet-Ruchea, Scott Sherrill-Mixb, Gerald H. Learna , Lindsey Plenderleithc , Andrew G. Smitha , Hannah J. Barbiana,b, Ronnie M. Russella,b, Marcos V. P. Gondima , Catherine Y. Baharia , Christiana M. Shawa , Yingying Lia , Timothy Deckera , Barton F. Haynesd,e,f, George M. Shawa,b, Paul M. Sharpc , Persephone Borrowg , and Beatrice H. Hahn
doi: 10.1073/pnas.1620144114

Hand-powered ultralow-cost paper centrifuge

M. Saad Bhamla, Brandon Benson, Chew Chai, Georgios Katsikis, Aanchal Johri & Manu Prakash
Nature Biomedical Engineering 1, Article number: 0009 (2017), doi:10.1038/s41551-016-0009

Lasing in blood

Yu-Cheng Chen, Qiushu Chen, and Xudong Fan
Optica 3, 809-815 (2016)

Detection of dengue NS1 antigen using long-range surface plasmon waveguides

Wei Ru Wong, Shamala Devi Sekaran, Faisal Rafiq Mahamd Adikan, Pierre Berini
Biosensors and Bioelectronic

Peptide-conjugated glass slides for selective capture and purification of diagnostic cells: Applications in urine cytology

Danuta B. Wronska, Magdalena Krajewska, Natalia Lygina, Juhua C. Morrison, Dalia Juzumiene, W. David Culp,Shrikumar A. Nair, Martyn Darby, and Christopher M. Hofmann
BioTechniques, Vol. 57, No. 2, August 2014, pp. 63–71

MDJ Libardo, TJ Paul, R Prabhakar, AM Angeles-Boza - Biochimie, 2015

Biochimie, April 2015

Successful Isolation of Viable Adipose-Derived Stem Cells from Human Adipose Tissue Subject to Long-Term Cryopreservation: Positive Implications for Adult Stem Cell-Based Therapeutics in Patients of Advanced Age

Sean M. Devitt, Cynthia M. Carter, Raia Dierov, Scott Weiss, Robert P. Gersch, and Ivona Percec
Stem Cells International Volume 2015, Article ID 146421, 11 pages

Recovered Plasma Publications

Human Whole Blood Publications

Human Dermal Fibroblasts Publications

Neonatal Fibroblasts Publications

Human Pericytes (hPC-PL) Publications

Human Skin Publications

ORAC Antioxidant Assay Kit Publications

The mycosporine-like amino acids porphyra-334 and shinorine are antioxidants and direct antagonists of Keap1-Nrf2 binding

Ranko Gacesa, Karl P.Lawrence, Nikolaos D.Georgakopoulos, Kazuo Yabe, Walter C. Dunlap, David J.Barlow, Geoffrey Wells, Antony R.Young, Paul F.Long
https://doi.org/10.1016/j.biochi.2018.07.020

Phenolics, antioxidants and color properties of aqueous pigmented plant extracts: Ardisia colorata var. elliptica, Clitoria ternatea, Garcinia mangostana and Syzygium cumini

A.M. Siti Azima , A. Noriham, N. Manshoor
https://doi.org/10.1016/j.jff.2017.09.018

Journal of Functional Foods

Angela R. Hillman, Bryna C.R. Taylor (nee Chrismas), Diahnn Thompkins
Journal of Functional Foods 29 (2017) 185–192

Extra Cellular Matrix (ECM) Coated Cell Culture Plastics Publications

Serum / Plasma Fatty Acid and Glycerol Detection Kits Publications

Involvement of a gut-retina axis in protection against dietary glycemia-induced age-related macular degeneration

Sheldon Rowana, Shuhong Jianga, Tal Koremb, Jedrzej Szymanskid, Min-Lee Changa, Jason Szeloga, Christa Cassalmane, Kalavathi Dasuria, Christina McGuiref, Ryoji Nagaig, Xue-Liang Duh, Michael Brownleeh, Naila Rabbanii, Paul J. Thornalleyi, James D. Balejaf, Amy A. Deikj, Kerry A. Piercej, Justin M. Scottj, Clary B. Clishj, Donald E. Smitha, Adina Weinbergerb,c, Tali Avnit-Sagib,c, Maya Lotan-Pompanb,c, Eran Segalb,c, and Allen Taylor
doi: 10.1073/pnas.1702302114

Dual 5-alpha reductase inhibition promotes hepatic lipid accumulation in man

Jonathan M. Hazlehurst (MBChB)1*, Andrei I. Oprescu, (PhD)2* Nikolaos Nikolaou, (MSc)1 Riccardo Di Guida, (BSc)3 Annabel E. K. Grinbergs4, Nigel P. Davies, (PhD)5 Robert B. Flintham, (MSc)5 Matthew J Armstrong, (PhD)6 Angela E. Taylor, (PhD)2 Beverly A. Hughes, (BSc)2 Jinglei Yu, (PhD)7 Leanne Hodson, (PhD)1 Warwick B. Dunn, (PhD)3, and Jeremy W. Tomlinson, (PhD, FRCP)1

The rs340874 PROX1 type 2 diabetes mellitus risk variant is associated with visceral fat accumulation and alterations in postprandial glucose and lipid metabolism

Adam Kretowski1, 2, Edyta Adamska2, Katarzyna Maliszewska1, Natalia Wawrusiewicz-Kurylonek1, Anna Citko1, 2, Joanna Goscik3, Witold Bauer1, 2, Juliusz Wilk1, Anna Golonko4, Magdalena Waszczeniuk1, 4, Danuta Lipinska1, Justyna Hryniewicka1, Magdalena Niemira2, Magdalena Paczkowska2, Michal Ciborowski2 and Maria Gorska1...
- Genes & nutrition, 2015.

Effects of intravenous glucose and lipids on innate immune cell activation in healthy, obese, and type 2 diabetic subjects

Peter Horvath, Stacy R. Oliver, Frank P. Zaldivar Jr, Shlomit Radom-Aizik & Pietro R. Galassetti
Physiol Rep, 3(2), 2015, e12249, doi: 10.14814/phy2.12249

Differences in metabolic and inflammatory responses in lower and upper body high-intensity intermittent exercise

Fábio S. Lira, Valéria L. G. Panissa, Ursula F. Julio, Emerson Franchini
European Journal of Applied Physiology
February 2015

Caulerpa lentillifera extract ameliorates insulin resistance and regulates glucose metabolismin C57BL/KsJ-db/db mice via PI3K/AKT signaling pathway in myocytes

Bhesh Raj Sharma (bhesh82@gmail.com) Hyun Jung Kim (hyunkim@mokpo.ac.kr) Dong Young Rhyu (rhyudy@mokpo.ac.kr)
Journal of Translational Medicine Sample doi:10.1186/s12967-015-0412-5

Human Stem Cells Publications

Glyco-engineered Long Acting FGF21 Variant with Optimal Pharmaceutical and Pharmacokinetic Properties to Enable Weekly to Twice Monthly Subcutaneous Dosing

Yan Weng, Tetsuya Ishino, Annette Sievers, Saswata Talukdar, Jeffrey R. Chabot, Amy Tam, Weili Duan, Kelvin Kerns, Eric Sousa, Tao He, Alison Logan, Darwin Lee, Dongmei Li, Yingjiang Zhou, Barbara Bernardo, Alison Joyce, Mania Kavosi, Denise M. O'Hara, Tracey Clark, Jie Guo, Craig Giragossian, Mark Stahl, Roberto A. Calle, Ron Kriz, Will Somers & Laura Lin
doi:10.1038/s41598-018-22456-w

Processing fixed and stored adipose-derived stem cells for quantitative protein array assays

Jessica S. Sadick and Eric M. Darling
BioTechniques, Vol. 63, No. 6, December 2017, pp. 275–280

MicroRNA-143 Regulates Adipocyte Differentiation.

Christine Esau, Xiaolin Kang, Eigen Peralta, Elaine Hanson, Eric G. Marcusson, Lingamanaidu V. Ravichandran, Yingqing Sun, Seongjoon Koo, Ranjan J. Perera, Ravi Jain, Nicholas M. Dean, Susan M. Freier, C. Frank Bennett, Bridget Lollo, and Richard Griffey J. Biol. Chem., Dec 2004; 279: 52361 - 52365.
J. C. Strum, J. H. Johnson, J. Ward, H. Xie, J. Feild, A. Hester, A. Alford and K. M. Waters Mol Endocrinol. 2009; 23 (11): 1876-84.
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