CELLnTEC Progenitor Cell Targeted (PCT) Technology

Improved isolation, proliferation and longevity. CELLnTEC's defined Progenitor Cell Targeted media provide all these benefits, enabling you to work faster and smarter.

How does Progenitor Cell Targeting work?

PCT media work by specifically targeting and retaining increased numbers of progenitor cells in vitro.

This figure shows the results of a FACS experiment, in which the percentage of double labeled progenitor cells was evaluated in both freshly isolated keratinocytes and in keratinocytes grown in CnT-07 for 3 passages.

In freshly isolated cells, 6% of the population were progenitor cells. After 3 passages, this had increased to 68%, a 10-fold increase.

This high retention and enrichment of progenitor cells enables of host of benefits for the researcher.

The Benefits of Progenitor Cell Targeting

  1. Cut your primary culture expansion time by up to one-third
    CELLnTEC's PCT culture media establish up to 5x more cells in primary culture by maximising progenitor cell retention and colony formation.

    For researchers, this means less waiting for early-passage cell cultures to expand, saving you days to weeks of lost preparation time.
  2. No more feeder cells, conditioned media or non-defined additives
    By accurately re-creating the characteristic environment of the in vivo stem cell niche, CELLnTEC media re no longer dependent on time-consuming and expensive non-defined additives such as feeder cells, conditioned media or bovine pituitary extract
  3. Extended in vitro lifespan
    In vivo, progenitor cells are responsible for the growth and maintenance of all tissues throughout the life of the organism.

    CELLnTEC culture media provide a precise environment that mimics the in vivo progenitor cell environment, thereby enabling extended maintenance of these cells in vitro
  4. Accurate modeling
    Progenitor cells drive growth and differentiation in all tissues. By targeting these essential cells in vitro, CELLnTEC cells and culture media provide a new standard of extended modelling accuracy in both primary and long-term cultures.
  5. Optimal comparability
    Eliminate inter-donor variability! With long-term, stable growth, CELLnTEC's long-term guarantee cell systems now enable optimal comparability over years of experimentation

The Progenitor Cell Advantage

Progenitor cells are found in all tissues, and are responsible for the growth and regeneration of those tissues throughout the life of the organism.

CELLnTEC's Progenitor Cell Targeting (PCT) technology mimics the adult stem cell niche, allowing us to establish in vitro systems with a striking suite of benefits.

For more details about these benefits, please see the following pages:

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