The majority of breast cancers originate in the lobular or ductal cells of the milk-producing glands. In these structures, there are two main cell types: the inner luminal cells surrounded by basal myoepithelium. These cells types are distinct and are the precursors to various forms of breast cancer. As such, it is important to study these cell populations independently as well as in co-culture models systems. ZenBio is proud to offer cryopresevered human mammary epithelial cells.
Cells have tested negative for HIV-1, HIV-2, HTLV-1, HTLV-2, HbsAG, HbcAB, HCV, and RPR.
Basal myoepithelial cell surround the luminal cells and have both contractile muscle and epithelial properties. Basal myoepithelial cells tend to dominate normal primary cultures. Additionally, basal-type breast cancers are typically estrogen and progesterone receptor negative.
Luminal cells line the apical surface of the normal breast duct and have secretory properties. Most breast cancers arise from luminal cells and are heterogeneous in their expression of hormone receptors and ERBB2 expression.
Human Mammary Cells
|MBE-F||Cryopreserved Mammary Basal Epithelial Cells, (0.5x106 cells/vial)||Vial||$623.00|
|MBE-F-TM||Cryopreserved Mammary Basal Epithelial Cells, (TUMOR Derived)(0.5x106 cells/vial)||Vial||$1126.00|
|MLE-F||Cryopreserved Mammary Luminal Epithelial Cells, (0.5x106 cells/vial)||Vial||$623.00|
|MLE-F-TM||Cryopreserved Mammary Luminal Epithelial Cells, (TUMOR Derived), (0.5x106 cells/vial)||Vial||$1126.00|
|MF-F||Cryopreserved Human Mammary Fibroblasts; (0.5x106 cells/vial)||Vial||$623.00|
|MEG-1||Mammary Epithelial Cell Growth Medium||500ml||$134.00|
|LCM-1||Mammary Luminal Growth Medium||500ml||$134.00|
|MF-1||Mammary Fibroblast Growth Medium||500ml||$119.00|
|MF-2||Mammary Fibroblast Basal Medium||500ml||$84.00|
|MFM-100||Mammary Fibroblast Cryopreservation Medium||100ml||$177.00|
ZenBio can provide Contract Services using our human mammary epithelial cell system. These services include Proliferation, Cytotoxicity, and Gene Expression Profiling. For a detail consultation, please: Contact Us
A comprehensive list of products and prices can be found at Retail Prices(.PDF).
Oral delivery of anti-MDM2 inhibitor SP141-loaded FcRn-targeted nanoparticles to treat breast cancer and metastasis
Jiang-Jiang Qina, b, Wei Wanga, b, Sushanta Sarkara, Ruiwen Zhang
Gastrointestinal Fibroblasts Have Specialized, Diverse Transcriptional Phenotypes: A Comprehensive Gene Expression Analysis of Human Fibroblasts
Youichi Higuchi , Motohiro Kojima , Genichiro Ishii, Kazuhiko Aoyagi, Hiroki Sasaki, Atsushi Ochiai
Published: June 5, 2015DOI: 10.1371/journal.pone.0129241