Human Stem Cells
ZenBio, a pioneer in the adult stem cell field, delivers quality, cost-effective adipose-derived stem cells in large enough quantities to meet a wide range of project demands. Each lot is evaluated and qualified to remain undifferentiated in culture or to differentiate into osteoblasts, chondrocytes or adipocytes upon exposure to specific differentiation media formulations.
As interest grows in the expanding field of stem cell research, areas such as regenerative medicine, tissue engineering and basic stem cell biology necessitate a reliable cost-effective cell-based tool for use in discovery and design projects. Adipose-derived adult stem cells and their unique differentiation properties can be utilized in any number of research applications and offer decided benefits over similar multipotent cell types.
Adipose tissue is typically in greater supply enabling ample sourcing for isolation and production of adult stem cells – at a fraction of the cost for bone marrow-derived counterparts while maintaining similar markers and characteristics. Adult stem cells offer another more subtle benefit allowing scientists to circumvent the ethical issues normally associated with employing embryonic stem cells in biomedical research.
ZenBio adult stem cells are available with optimized media formulations to maximize growth, survival and differentiation in culture. All cells have been screened negative for HIV-1, HIV-2, HTLC-1, HTLV-2, Hep-B, Hep-C, and mycoplama.
Adult stem cells differentiated into adipocytes. Cells shown are two weeks old and have been stained with the neutral lipid dye Oil Red O. | |
Adult stem cells differentiated into osteoblasts. Mineralized cells stained with Alizarin Red. | |
Adult stem cells differentiated into chondrocytes. Cells stained with Alcian Blue. |
Ordering Information:
Human Stem Cells
Item# | Item Desc | U/M | Price |
---|---|---|---|
ASC-F | Cryopreserved Adipose derived Adult Stem Cells, 1 million cells/vial | Vial | $495.00 |
ASC-F-SL | Cryopreserved Adipose derived Adult Stem Cells (POOLED), 1 million cells/vial | Vial | $495.00 |
SER-BMCD34-F | Cryopreserved Human Bone Marrow CD34+ Cells, Cryopreserved, Single Donor, 0.5 million cells/vial | Vial | $925.00 |
HBMMSC-F | Cryopreserved Human Bone Marrow derived Mesenchymal Stem Cells, 1 million cells/vial | Vial | $918.00 |
PLMSC-F | Cryopreserved Human Placental Derived Mesenchymal Stem Cells, 0.5 million/vial | Vial | $643.00 |
MSCG-1 | Mesenchymal Stem Cell Growth Medium, (for use with Placental) | 500ml | $136.00 |
BMSC-1 | Bone Marrow Stem Cell Growth Medium | 500ml | $188.00 |
DM-2 | Adipocyte Differentiation Medium | 100ml | $145.00 |
DM-2-500 | Adipocyte Differentiation Medium | 500ml | $626.00 |
AM-1 | Adipocyte Maintenance Medium | 500ml | $136.00 |
OB-1 | Osteoblast Differentiation Medium for Adipose Derived | 500ml | $170.00 |
HBMOB-1 | Osteoblast Differentiation Media for Bone Barrow Mesenchymal Stem Cells 500ml | 500ml | $170.00 |
CM-1-100 | Chondrocyte Differentiation Medium | 100ml | $374.00 |
CM-1 | Chondrocyte Differentiation Medium | 500ml | $1820.00 |
FM-1-100 | Cryopreservation Medium | 100ml | $242.00 |
Contact Us For More Information
A comprehensive list of products and prices can be found at Retail Prices (.PDF).
Human Stem Cells Publications
Intranasal delivery of exosomes from human adipose derived stem cells at forty-eight hours post injury reduces motor and cognitive impairments following traumatic
Lauren D.Moss, Derek Sode, Rekha Patel, Ashley Lui, Charles Hudson, Niketa A. Patel, Paula C. BickfordDOI: https://doi.org/10.1016/j.neuint.2021.105173
CC chemokine ligand 2 (CCL2) stimulates aromatase gene expression in mammary adipose tissue
Gabriela MartÃnez-Chacón, Emrah Yatkin, Lauri Polari, Defne Deniz Din&ccilde;, Emilia Peuhu, Pauliina Hartiala, Niina Saarinen, Sari Mäkelähttps://doi.org/10.1096/fj.201902485RRR
Quantification of Antibody Persistence for Cell Surface Protein Labeling
Megan E. Dempsey, Olivia Woodford-Berry & Eric M. DarlingDOI: https://doi.org/10.1007/s12195-021-00670-3
Surface-Triggered In Situ Gelation for Tunable Conformal Hydrogel Coating of Therapeutic Cells and Biomedical Devices Tung Thanh Pham, Phuong Le Tran, Cao
Tung Thanh Pham, Phuong Le Tran, Cao Dai Phung, Hanh Thuy Nguyen, Canh Hung Nguyen, Chul Soon Yong, Jong Oh Kim, Simmyung Yook, and Jee-Heon JeongAdv. Funct. Mater., DOI: 10.1002/adfm.202010169
Heterospheroid formation improves therapeutic efficacy of mesenchymal stem cells in murine colitis through immunomodulation and epithelial regeneration
Shobha Regmi, Yoogin Seo, Ji-Su Ahn, Shiva Pathak, Suman Acharya, Tiep Tien Nguyen, Simmyung Yook, Jong-Hyuk Sung, Jun-Beom Park, Jong Oh Kim, Chul Soon Young, Hyung-Sik Kim, Jee-Heon Jeonghttps://doi.org/10.1016/j.biomaterials.2021.120752
Cellular Mechanism Underlying Highly-Active or Antiretroviral Therapy-Induced Lipodystrophy: Atazanavir, a Protease Inhibitor, Compromises Adipogenic Conversion ...
Sadanori Akita, Keiji Suzuki, Hiroshi Yoshimoto, Akira Ohtsuru, Akiyoshi Hirano and Shunichi YamashitaInt. J. Mol. Sci. 2021, 22(4), 2114; https://doi.org/10.3390/ijms22042114
Force sensors for measuring microenvironmental forces during mesenchymal condensation
Robert A. Gutierrez, Wenqiang Fang, Haneesh Kesari, Eric M.Darlinghttps://doi.org/10.1016/j.biomaterials.2021.120684
Accelerated subcutaneous abdominal stem cell adipogenesis predicts insulin sensitivity in normal-weight women with polycystic ovary syndrome
Daniel A. Dumesic, Ayli Tulberg, Karen L. Leung, Samantha C. Fisch, Tristan R. Grogan, David H. Abbott, Rajanigandha Naik, aGregorio D. Chazenbalkhttps://doi.org/10.1016/j.fertnstert.2020.10.003
Human stem cell response to layered zirconium phosphate
Jin Nakamura, Kanta Endo, Ayae Sugawara-Narutaki and Chikara OhtsukiDOI: 10.1039/D0RA04924G (Paper) RSC Adv., 2020, 10, 36051-36057
Chitosan-cartilage extracellular matrix hybrid scaffold induces chondrogenic differentiation to adipose-derived stem cells
I-Chan Lin, Tsung-Jen Wang, Chien-Liang Wu, Dai-Hua Lu, Yi-Ru Chen, Kai-Chiang Yanghttps://doi.org/10.1016/j.reth.2020.03.014
The Survey of Cells Responsible for Heterotopic Ossification Development in Skeletal Muscles-Human and Mouse Models
Łukasz Pulik, Bartosz Mierzejewski, Maria A. Ciemerych, Edyta Brzóska, and Paweł ŁÄgoszCells 2020, 9, 1324; doi: 10.3390/cells9061324
Three-dimensional imaging of cell and extracellular matrix elasticity using quantitative micro-elastography
MATT S. HEPBURN, PHILIP WIJESINGHE, LUKE G. MAJOR, JIAYUE LI, ALIREZA MOWLA, CHRISSIE ASTELL, HYUN WOO PARK, YONGSUNG HWANG, YU SUK CHOI, AND BRENDAN F. KENNEDYhttps://doi.org/10.1364/BOE.383419
Stem Cell Mechanosensation on Gelatin Methacryloyl (GelMA) Stiffness Gradient Hydrogels
Claire Kim, Jennifer L. Young, Andrew W. Holle, Kwanghee Jeong, Luke G. Major, Ji Hoon Jeong, Zachary M. Aman, Dong-Wook Han, Yongsung Hwang, Joachim P. Spatz, Yu Suk ChoiDOI: https://doi.org/10.1007/s10439-019-02428-5
Adipose-derived stromal/stem cells improve epidermal homeostasis
Mariko Moriyama, Shunya Sahara, Kaori Zaiki, Ayumi Ueno, Koichi Nakaoji, Kazuhiko Hamada, Toshiyuki Ozawa, Daisuke Tsuruta, Takao Hayakawa & Hiroyuki MoriyamaDOI: https://doi.org/10.1038/s41598-019-54797-5
Volume adaptation controls stem cell mechanotransduction
Luke G Major, Andrew W Holle, Jennifer L Young, Matt S Hepburn, Kwanghee Jeong, Ian L Chin, Rowan W Sanderson, Ji Hoon Jeong, Zachary M. Aman, Brendan F Kennedy, Yongsung Hwang, Dong-Wook Han, Hyun Woo Park, Kun-Liang Guan, Joachim P Spatz, Yu Suk Choihttps://doi.org/10.1021/acsami.9b19770
Intraportally delivered stem cell spheroids localize in the liver and protect hepatocytes against GalN/LPS-induced fulminant hepatic toxicity
Shobha Regmi, Shiva Pathak, Tung Pham Thanh, Tiep Tien Nguyen, Jong-Hyuk Sung, Simmyung Yook, Jong Oh. Kim, Chul Soon Yong, Inho Choi, Kyoung-Oh Doh, Pil-Hoon Park, Jun-Beom Park, Yoojin Seo, Bieong-Kil Kim, Dong-Mok Lee, Ik-Jae Moon, Hyung-Sik Kim & Jee-Heon Jeonghttps://doi.org/10.1186/s13287-019-1337-3
Comparing the use of differentiated adipose-derived stem cells and mature adipocytes to model adipose tissue in vitro
Ann-Cathrin Volz, Birgit Omengo, Sandra Gehrke, Petra Juliane Klugerhttps://doi.org/10.1016/j.diff.2019.09.002
Design of experiments to assess the effect of culture parameters on the osteogenic differentiation of human adipose stromal cells
Mirasbek Kuterbekov, Paul Machillot, Francis Baillet, Alain M. Jonas, Karine Glinel & Catherine PicartDOI https://doi.org/10.1186/s13287-019-1333-7
Preparation of skin tissue engineering scaffold based on Adipose-derived Tissue
Sanaz Samani, Mohammad Ali Shokrgozar, Arash Zamini, Mohammad Majidi, Hossein Tavassoli, Amir Aidun, Shahin BonakdarDOI: 10.22034/jtm.2019.83230
Involvement of P2X7 Receptors in the Osteogenic Differentiation of Mesenchymal Stromal/Stem Cells Derived from Human Subcutaneous Adipose Tissue
Marzia Carluccio, Mariachiara Zuccarini, Sihana Ziberi, Patricia Giuliani, Caterina Morabito, Maria A. Mariggiò, Maria Teresa Lonardo, Elena Adinolfi, Elisa Orioli, Patrizia Di Iorio, Francesco Caciagli, Renata CiccarelliDOI: https://doi.org/10.1007/s12015-019-09883-6
Rapid molecular detection of macrolide resistance
Megan M. Nelson, Christopher L. Waldron and John R. Brachthttps://doi.org/10.1186/s12879-019-3762-4
Adipose stem cell crosstalk with chemo-residual breast cancer cells: implications for tumor recurrence
Matthew A. Lyes, Sturgis Payne, Paul Ferrell, Salvatore V. Pizzo, Scott T. Hollenbeck, Robin E. Bachelderhttps://doi.org/10.1007/s10549-018-05103-w
Peroxisome proliferator-activated receptor-α agonist and all-trans retinoic acid induce epithelial differentiation of subcutaneous adiposeâderived stem cells from debrided burn skin
Shanmugasundaram Natesan, Nicole L. Wrice, Robert J. Christyhttps://doi.org/10.1002/jcb.28197
Adipose-derived stem cell-secreted factors promote early stage follicle development in a biomimetic matrix
Claire E Tomaszewski, Elizabeth Constance, Melissa M Lemke, Hong Zhou, Vasantha Padmanabhan, Kelly B. Arnold and Ariella ShikanovBiomater. Sci., 2018, DOI 10.1039/C8BM01253A
Prostaglandin E2down-regulates sirtuin 1 (SIRT1) leading to elevated levels of aromatase, providing insights into the obesity-breast cancer connection*
Kotha Subbaramaiah, Neil M Iyengar, Monica Morrow, Olivier Elemento, Xi Kathy Zhou and Andrew J. Dannenbergdoi: 10.1074/jbc.RA118.005866, jbc.RA118.005866.
nterplay of topographical and biochemical cues in regulating osteoblast cellular activity in BMPâ2 eluting threeâdimensional cellular titanium alloy mesh structures
Krishna Chaitanya Nune, R. Devesh Kumar Misra, Yun Bai, Shujun Li, Rui Yanghttps://doi.org/10.1002/jbm.a.36520
Pneumatospinning of collagen microfibers from benign solvents
Seth Polk, Nardos Sori, Nick Thayer, Nathan Kemper, Yas Maghdouri-White, Anna A Bulysheva, and Michael P FrancisBiofabrication 10 045004
Long noncoding RNA MALAT1 in exosomes drives regenerative function and modulates inflammation-linked networks following traumatic brain injury
Niketa A. Patel, Lauren Daly Moss, Jea-Young Lee, Naoki Tajiri, Sandra Acosta, Charles Hudson, Sajan Parag, Denise R. Cooper, Cesario V. Borlongan and Paula C. BickfordDiscovery of a stem-like multipotent cell fate
Emily S Paffhausen, Yasir Alowais, Cara W Chao, Evan C Callihan, Karen Creswell, and John R BrachtAm J Stem Cells. 2018; 7(2): 25–37.
Human Adipose-Derived Stem Cell Conditioned Media and Exosomes Containing MALAT1 Promote Human Dermal Fibroblast Migration and Ischemic Wound Healing
Cooper Denise R., Wang Chunyan, Patel Rehka, Trujillo Andrea, Patel Niketa A., Prather Jamie, Gould Lisa J., and Wu Mack H.https://doi.org/10.1089/wound.2017.0775
Cell Mimicking Microparticles Influence the Organization, Growth, and Mechanophenotype of Stem Cell Spheroids
Nicholas R. Labriola, Jessica S. Sadick, Jeffrey R. Morgan, Edith Mathiowitz, Eric M. DarlingDOI https://doi.org/10.1007/s10439-018-2028-4
Cigarette Smoking Impairs Adipose Stromal Cell Vasculogenic Activity and Abrogates Potency to Ameliorate Ischemia
Daria Barwinska, Dmitry O. Traktuev, Stephanie Merfeld-Clauss, Todd G. Cook, Hongyan Lu, Irina Petrache, Keith L. MarchGlyco-engineered Long Acting FGF21 Variant with Optimal Pharmaceutical and Pharmacokinetic Properties to Enable Weekly to Twice Monthly Subcutaneous Dosing
Yan Weng, Tetsuya Ishino, Annette Sievers, Saswata Talukdar, Jeffrey R. Chabot, Amy Tam, Weili Duan, Kelvin Kerns, Eric Sousa, Tao He, Alison Logan, Darwin Lee, Dongmei Li, Yingjiang Zhou, Barbara Bernardo, Alison Joyce, Mania Kavosi, Denise M. O'Hara, Tracey Clark, Jie Guo, Craig Giragossian, Mark Stahl, Roberto A. Calle, Ron Kriz, Will Somers & Laura Lindoi:10.1038/s41598-018-22456-w
L-10 suppresses TNF-α-induced expression of human aromatase gene in mammary adipose tissue
Gabriela MartÃnez-Chacón, Kristy A. Brown, Maria M. Docanto, Himanshu Kumar, Seppo Salminen, Niina Saarinen, and Sari Mäkelähttps://doi.org/10.1096/fj.201700938RRR
Processing fixed and stored adipose-derived stem cells for quantitative protein array assays
Jessica S. Sadick and Eric M. DarlingBioTechniques, Vol. 63, No. 6, December 2017, pp. 275–280
Impact of isolation method on doubling time and the quality of chondrocyte and osteoblast differentiated from murine dental pulp stem cells
Rohaya Megat Abdul Wahab, Nur Akmal Mohamed Rozali, Sahidan Senafi, Intan Zarina Zainol Abidin, Zaidah Zainal Ariffin, Shahrul Hisham Zainal Ariffin10.7717/peerj.3180
Mechanical Properties and Cell Compatibility of Agarose Hydrogels Containing Proteoglycan Mimetic Graft Copolymers
Hannah M. Pauly, Laura W. Place, Tammy L. Haut Donahue, and Matt J KipperDOI: 10.1021/acs.biomac.7b00643
Persistence and proliferation of human mesenchymal stromal cells in the right ventricular myocardium after intracoronary injection in a large animal model of ...
Roza Badr Eslam, Kevin Croce, Fernanda Marinho Mangione, Robert Musmann, Jane A. Leopold, Richard N. Mitchell, Aaron B. Waxmanhttp://doi.org/10.1016/j.jcyt.2017.03.002
Human Adipose-Derived Stem Cells Labeled with Plasmonic Gold Nanostars for Cellular Tracking and Photothermal Cancer Cell Ablation
Shammas, Ronnie L. B.S.; Fales, Andrew M. B.S.; Crawford, Bridget M. B.S.; Wisdom, Amy J. B.S.; Devi, Gayathri R. Ph.D.; Brown, David A. M.D., Ph.D.; Vo-Dinh, Tuan Ph.D.; Hollenbeck, Scott T. M.D.doi: 10.1097/PRS.0000000000003187
Osteoblast cellular activity on low elastic modulus Ti–24Nb–4Zr–8Sn alloy
K.C. Nunea, R.D.K. Misraa, S.J. Lib, Y.L. Haob, R. Yangbhttp://dx.doi.org/10.1016/j.dental.2016.11.005
Functional response of osteoblasts in functionally gradient titanium alloy mesh arrays processed by 3D additive manufacturing
K.C. Nunea, A. Kumara, R.D.K. Misraa, S.J. Lib, Y.L. Haob, R. Yanghttp://dx.doi.org/10.1016/j.colsurfb.2016.09.050
Ligand Independent and Subtype-Selective Actions of Thyroid Hormone Receptors in Human Adipose Derived Stem Cells
Aleksandra Cvoro, Aleksandar Bajic, Aijun Zhang, Marisa Simon, Igor Golic, Douglas H. Sieglaff, Mirjana Maletic-Savatic, Aleksandra Korac, Paul WebbPublished: October 12, 2016 http://dx.doi.org/10.1371/journal.pone.0164407
Screening ToxCast™ prioritized chemicals for PPARG function in a human adipose-derived stem cell model of adipogenesis
Briana Foley, Daniel Doheny, Michael Black, Salil N. Pendse, Barbara Wetmore, Rebecca Clewell, Melvin E. Andersen, and Chad DeisenrothToxicol. Sci. (2016)doi: 10.1093/toxsci/kfw186
Anatomically shaped tissue-engineered cartilage with tunable and inducible anticytokine delivery for biological joint resurfacing
Franklin T. Moutosa, Katherine A. Glassb,c,d, Sarah A. Comptona, Alison K. Rossb,c, Charles A. Gersbachd, Farshid Guilaka, and Bradley T. Estesdoi: 10.1073/pnas.1601639113
In situ characterization of the mTORC1 during adipogenesis of human adult stem cells on chip
Xuanye Wua,b, Nils Schneidera,b, Alina Platena,b, Indranil Mitraa,b, Matthias Blazeka,b, Roland Zengerleb,c, Roland Schüleb,d,e, and Matthias Meierdoi: 10.1073/pnas.1601207113
STEM CELL EPIGENETICS, GENOMICS, AND PROTEOMICS
AXELLE LORIOT, a SVEN REISTER, a GREGORY K. PARVIZI, a PHILIPPE A. LYSY, b CHARLES DE SMETSTEM CELLS 2009;27:822–824
Biological functionality and mechanistic contribution of extracellular matrix-ornamented three dimensional Ti-6Al-4V mesh scaffolds
A. Kumar, K.C. Nune and R.D.K. MisraDOI: 10.1002/jbm.a.35809
The functional response of bioactive titania modified three-dimensional Ti-6Al-4V mesh structure toward providing a favorable pathway for intercellular ...
K.C. Nune, R.D.K. Misra, S.J. Li2, Y.L. Hao and W. ZhangDOI: 10.1002/jbm.a.35789
Mechanical Properties and Cellular Response of Novel Electrospun Nanofibers for Ligament Tissue Engineering: Effects of Orientation and Geometry
Hannah M. Paulya, Daniel J. Kellyb, c, d, e, Ketul C. Popata, f, Nathan A. Trujillof, Nicholas J. Dunneg, h, Helen O. McCarthyi, Tammy L. Haut Donahuedoi:10.1016/j.jmbbm.2016.03.022
Validation of Housekeeping Genes to Study Human Gingival Stem Cells and Their In Vitro Osteogenic Differentiation Using Real-Time RT-qPCR
Ihsène Ta\hi, Ali Nassif, Tsouria Berbar, Juliane Isaac, Ariane Berdal, Bruno Gogly, and Benjamin Philippe FournierStem Cells International Article ID 718046
Interplay between Self-assembled Structure of Bone Morphogenetic Protein-2 (BMP-2) and Osteoblast Functions in Three-Dimensional Titanium Alloy Scaffolds: Stimulation of Osteogenic Activity
K.C. Nune, A. Kumar, L.E. Murr and R.D.K. MisraDOI: 10.1002/jbm.a.35592
Detection of early stage changes associated with adipogenesis using Raman spectroscopy under aseptic conditions
Adam Mitchell, Lorna Ashton, Xuebin B. Yang, Royston Goodacre, Alistair Smith and Jennifer KirkhamArticle first published online: 6 OCT 2015
DOI: 10.1002/cyto.a.22777
Validation of Housekeeping Genes to Study Human Gingival Stem Cells and Their in Vitro Osteogenic Differentiation Using Real-Time RT-qPCR.
Ihséne Taïhi1, Ali Nassif, Tsouria Berbar, Juliane Isaac, Ariane Berdal1, Bruno Gogly, Benjamin Philippe FournierMesenchymal Stem Cell–Like Properties of Orbital Fibroblasts in Graves' OrbitopathyMesenchymal Stem Cells in Grave's Orbitopathy
Katarzyna Kozdon; Caroline Fitchett; Geoffrey E. Rose; Daniel G. Ezra; Maryse BaillyInvestigative Ophthalmology & Visual Science September 2015, Vol.56, 5743-5750. doi:10.1167/iovs.15-16580
Characteristic expression of MSX1, MSX2, TBX2 and ENTPD1 in dental pulp cells
Sakiko Fujii Katsumi Fujimoto Noriko Goto Masami Kanawa Takeshi Kawamoto Haiou Pan Petcharin Srivatanakul Waralak Rakdang Juthamas Pornprasitwech Tania Saskianti Ketut Suardita Fusanori Nishimura Yukio KatoBiomedical Reports, 2015
Fact versus artifact: Avoiding erroneous estimates of sulfated glycosaminoglycan content using the dimethylmethylene blue colorimetric assay for tissue-engineered ...
C.H. Zheng and M.E. LevenstonEuropean Cells and Materials Vol. 29 2015 (pages 224-236), ISSN 1473-2262
3D hydrogel model using adipose-derived stem cells for vocal fold augmentation.
H. Park, S. Karajanagi, K. Wolak, J. Aanestad, L. Deheron, J. Kobler, G. Lopez-Guerra, J. Heaton, R. S. Langer and S. Zeitels Tissue Eng Part A 2010; 16:535-543.Impaired Activation of Protein Kinase C- by Insulin and Phosphatidylinositol-3,4,5-(PO4)3 in Cultured Preadipocyte-Derived Adipocytes and Myotubes of Obese Subjects.
M. P. Sajan, M. L. Standaert, A. Miura, G. Bandyopadhyay, P. Vollenweider, D. M. Franklin, R. Lea-Currie, and R. V. Farese J. Clin. Endocrinol. Metab., Aug 2004; 89: 3994 - 3998.Adipose-Derived Stem Cells for Regenerative Medicine.
Jeffrey M. Gimble, Adam J. Katz, and Bruce A. Bunnell Circ. Res., May 2007; 100: 1249 - 1260.MicroRNA-143 Regulates Adipocyte Differentiation.
Christine Esau, Xiaolin Kang, Eigen Peralta, Elaine Hanson, Eric G. Marcusson, Lingamanaidu V. Ravichandran, Yingqing Sun, Seongjoon Koo, Ranjan J. Perera, Ravi Jain, Nicholas M. Dean, Susan M. Freier, C. Frank Bennett, Bridget Lollo, and Richard Griffey J. Biol. Chem., Dec 2004; 279: 52361 - 52365.J. C. Strum, J. H. Johnson, J. Ward, H. Xie, J. Feild, A. Hester, A. Alford and K. M. Waters Mol Endocrinol. 2009; 23 (11): 1876-84.