Human Stem Cells
ZenBio, a pioneer in the adult stem cell field, delivers quality, cost-effective adipose-derived stem cells in large enough quantities to meet a wide range of project demands. Each lot is evaluated and qualified to remain undifferentiated in culture or to differentiate into osteoblasts, chondrocytes or adipocytes upon exposure to specific differentiation media formulations.
As interest grows in the expanding field of stem cell research, areas such as regenerative medicine, tissue engineering and basic stem cell biology necessitate a reliable cost-effective cell-based tool for use in discovery and design projects. Adipose-derived adult stem cells and their unique differentiation properties can be utilized in any number of research applications and offer decided benefits over similar multipotent cell types.
Adipose tissue is typically in greater supply enabling ample sourcing for isolation and production of adult stem cells – at a fraction of the cost for bone marrow-derived counterparts while maintaining similar markers and characteristics. Adult stem cells offer another more subtle benefit allowing scientists to circumvent the ethical issues normally associated with employing embryonic stem cells in biomedical research.
ZenBio adult stem cells are available with optimized media formulations to maximize growth, survival and differentiation in culture. All cells have been screened negative for HIV-1, HIV-2, HTLC-1, HTLV-2, Hep-B, Hep-C, and mycoplama.
|Adult stem cells differentiated into adipocytes. Cells shown are two weeks old and have been stained with the neutral lipid dye Oil Red O.|
|Adult stem cells differentiated into osteoblasts. Mineralized cells stained with Alizarin Red.|
|Adult stem cells differentiated into chondrocytes. Cells stained with Alcian Blue.|
Human Stem Cells
|ASC-F||Cryopreserved Adipose derived Adult Stem Cells, 1 million cells/vial||Vial||$248.00|
|ASC-F-SL||Cryopreserved Adipose derived Adult Stem Cells (POOLED), 1 million cells/vial||Vial||$248.00|
|HBMMSC-F||Cryopreserved Human Bone Marrow derived Mesenchymal Stem Cells, 1 million cells/vial||Vial||$691.00|
|PLMSC-F||Cryopreserved Human Placental Derived Mesenchymal Stem Cells, 0.5 million/vial||Vial||$500.00|
|MSCG-1||Mesenchymal Stem Cell Growth Medium, (for use with Placental)||500ml||$96.00|
|BMSC-1||Bone Marrow Stem Cell Growth Medium||500ml||$133.00|
|DM-2||Adipocyte Differentiation Medium||100ml||$103.00|
|DM-2-500||Adipocyte Differentiation Medium||500ml||$442.00|
|AM-1||Adipocyte Maintenance Medium||500ml||$96.00|
|OB-1||Osteoblast Differentiation Medium for Adipose Derived||500ml||$119.00|
|HBMOB-1||Osteoblast Differentiation Media for Bone Barrow Mesenchymal Stem Cells 500ml||500ml||$119.00|
|CM-1-100||Chondrocyte Differentiation Medium||100ml||$265.00|
|CM-1||Chondrocyte Differentiation Medium||500ml||$1287.00|
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A comprehensive list of products and prices can be found at Retail Prices (.PDF).
Involvement of P2X7 Receptors in the Osteogenic Differentiation of Mesenchymal Stromal/Stem Cells Derived from Human Subcutaneous Adipose TissueMarzia Carluccio, Mariachiara Zuccarini, Sihana Ziberi, Patricia Giuliani, Caterina Morabito, Maria A. MariggiÃ², Maria Teresa Lonardo, Elena Adinolfi, Elisa Orioli, Patrizia Di Iorio, Francesco Caciagli, Renata Ciccarelli
Adipose stem cell crosstalk with chemo-residual breast cancer cells: implications for tumor recurrenceMatthew A. Lyes, Sturgis Payne, Paul Ferrell, Salvatore V. Pizzo, Scott T. Hollenbeck, Robin E. Bachelder
Peroxisome proliferator-activated receptor-α agonist and all-trans retinoic acid induce epithelial differentiation of subcutaneous adiposeâderived stem cells from debrided burn skinShanmugasundaram Natesan, Nicole L. Wrice, Robert J. Christy
Adipose-derived stem cell-secreted factors promote early stage follicle development in a biomimetic matrixClaire E Tomaszewski, Elizabeth Constance, Melissa M Lemke, Hong Zhou, Vasantha Padmanabhan, Kelly B. Arnold and Ariella Shikanov
Biomater. Sci., 2018, DOI 10.1039/C8BM01253A
Prostaglandin E2down-regulates sirtuin 1 (SIRT1) leading to elevated levels of aromatase, providing insights into the obesity-breast cancer connection*Kotha Subbaramaiah, Neil M Iyengar, Monica Morrow, Olivier Elemento, Xi Kathy Zhou and Andrew J. Dannenberg
doi: 10.1074/jbc.RA118.005866, jbc.RA118.005866.
nterplay of topographical and biochemical cues in regulating osteoblast cellular activity in BMPâ2 eluting threeâdimensional cellular titanium alloy mesh structuresKrishna Chaitanya Nune, R. Devesh Kumar Misra, Yun Bai, Shujun Li, Rui Yang
Biofabrication 10 045004
Am J Stem Cells. 2018; 7(2): 25–37.
Human Adipose-Derived Stem Cell Conditioned Media and Exosomes Containing MALAT1 Promote Human Dermal Fibroblast Migration and Ischemic Wound HealingCooper Denise R., Wang Chunyan, Patel Rehka, Trujillo Andrea, Patel Niketa A., Prather Jamie, Gould Lisa J., and Wu Mack H.
Cell Mimicking Microparticles Influence the Organization, Growth, and Mechanophenotype of Stem Cell SpheroidsNicholas R. Labriola, Jessica S. Sadick, Jeffrey R. Morgan, Edith Mathiowitz, Eric M. Darling
Glyco-engineered Long Acting FGF21 Variant with Optimal Pharmaceutical and Pharmacokinetic Properties to Enable Weekly to Twice Monthly Subcutaneous DosingYan Weng, Tetsuya Ishino, Annette Sievers, Saswata Talukdar, Jeffrey R. Chabot, Amy Tam, Weili Duan, Kelvin Kerns, Eric Sousa, Tao He, Alison Logan, Darwin Lee, Dongmei Li, Yingjiang Zhou, Barbara Bernardo, Alison Joyce, Mania Kavosi, Denise M. O'Hara, Tracey Clark, Jie Guo, Craig Giragossian, Mark Stahl, Roberto A. Calle, Ron Kriz, Will Somers & Laura Lin
Processing fixed and stored adipose-derived stem cells for quantitative protein array assaysJessica S. Sadick and Eric M. Darling
BioTechniques, Vol. 63, No. 6, December 2017, pp. 275–280
Impact of isolation method on doubling time and the quality of chondrocyte and osteoblast differentiated from murine dental pulp stem cellsRohaya Megat Abdul Wahab, Nur Akmal Mohamed Rozali , Sahidan Senafi, Intan Zarina Zainol Abidin, Zaidah Zainal Ariffin, Shahrul Hisham Zainal Ariffin
Mechanical Properties and Cell Compatibility of Agarose Hydrogels Containing Proteoglycan Mimetic Graft CopolymersHannah M. Pauly, Laura W. Place, Tammy L. Haut Donahue, and Matt J Kipper
Persistence and proliferation of human mesenchymal stromal cells in the right ventricular myocardium after intracoronary injection in a large animal model of ...Roza Badr Eslam, Kevin Croce, Fernanda Marinho Mangione, Robert Musmann, Jane A. Leopold, Richard N. Mitchell, Aaron B. Waxman
Human Adipose-Derived Stem Cells Labeled with Plasmonic Gold Nanostars for Cellular Tracking and Photothermal Cancer Cell AblationShammas, Ronnie L. B.S.; Fales, Andrew M. B.S.; Crawford, Bridget M. B.S.; Wisdom, Amy J. B.S.; Devi, Gayathri R. Ph.D.; Brown, David A. M.D., Ph.D.; Vo-Dinh, Tuan Ph.D.; Hollenbeck, Scott T. M.D.
Functional response of osteoblasts in functionally gradient titanium alloy mesh arrays processed by 3D additive manufacturingK.C. Nunea, A. Kumara, R.D.K. Misraa, S.J. Lib, Y.L. Haob, R. Yang
Ligand Independent and Subtype-Selective Actions of Thyroid Hormone Receptors in Human Adipose Derived Stem CellsAleksandra Cvoro, Aleksandar Bajic, Aijun Zhang, Marisa Simon, Igor Golic, Douglas H. Sieglaff, Mirjana Maletic-Savatic, Aleksandra Korac, Paul Webb
Published: October 12, 2016 http://dx.doi.org/10.1371/journal.pone.0164407
Screening ToxCast™ prioritized chemicals for PPARG function in a human adipose-derived stem cell model of adipogenesisBriana Foley, Daniel Doheny, Michael Black, Salil N. Pendse, Barbara Wetmore, Rebecca Clewell, Melvin E. Andersen, and Chad Deisenroth
Toxicol. Sci. (2016)doi: 10.1093/toxsci/kfw186
Anatomically shaped tissue-engineered cartilage with tunable and inducible anticytokine delivery for biological joint resurfacingFranklin T. Moutosa, Katherine A. Glassb,c,d, Sarah A. Comptona, Alison K. Rossb,c, Charles A. Gersbachd, Farshid Guilaka, and Bradley T. Estes
STEM CELLS 2009;27:822–824
Biological functionality and mechanistic contribution of extracellular matrix-ornamented three dimensional Ti-6Al-4V mesh scaffoldsA. Kumar, K.C. Nune and R.D.K. Misra
The functional response of bioactive titania modified three-dimensional Ti-6Al-4V mesh structure toward providing a favorable pathway for intercellular ...K.C. Nune, R.D.K. Misra, S.J. Li2, Y.L. Hao and W. Zhang
Mechanical Properties and Cellular Response of Novel Electrospun Nanofibers for Ligament Tissue Engineering: Effects of Orientation and GeometryHannah M. Paulya, Daniel J. Kellyb, c, d, e, Ketul C. Popata, f, Nathan A. Trujillof, Nicholas J. Dunneg, h, Helen O. McCarthyi, Tammy L. Haut Donahue
Validation of Housekeeping Genes to Study Human Gingival Stem Cells and Their In Vitro Osteogenic Differentiation Using Real-Time RT-qPCRIhsène Ta\hi, Ali Nassif, Tsouria Berbar, Juliane Isaac, Ariane Berdal, Bruno Gogly, and Benjamin Philippe Fournier
Stem Cells International Article ID 718046
Interplay between Self-assembled Structure of Bone Morphogenetic Protein-2 (BMP-2) and Osteoblast Functions in Three-Dimensional Titanium Alloy Scaffolds: Stimulation of Osteogenic ActivityK.C. Nune, A. Kumar, L.E. Murr and R.D.K. Misra
Detection of early stage changes associated with adipogenesis using Raman spectroscopy under aseptic conditionsAdam Mitchell, Lorna Ashton, Xuebin B. Yang, Royston Goodacre, Alistair Smith and Jennifer Kirkham
Article first published online: 6 OCT 2015
Validation of Housekeeping Genes to Study Human Gingival Stem Cells and Their in Vitro Osteogenic Differentiation Using Real-Time RT-qPCR.Ihséne Taïhi1, Ali Nassif, Tsouria Berbar, Juliane Isaac , Ariane Berdal1, Bruno Gogly, Benjamin Philippe Fournier
Mesenchymal Stem Cell–Like Properties of Orbital Fibroblasts in Graves' OrbitopathyMesenchymal Stem Cells in Grave's OrbitopathyKatarzyna Kozdon; Caroline Fitchett; Geoffrey E. Rose; Daniel G. Ezra; Maryse Bailly
Investigative Ophthalmology & Visual Science September 2015, Vol.56, 5743-5750. doi:10.1167/iovs.15-16580
Biomedical Reports, 2015
Fact versus artifact: Avoiding erroneous estimates of sulfated glycosaminoglycan content using the dimethylmethylene blue colorimetric assay for tissue-engineered ...C.H. Zheng and M.E. Levenston
European Cells and Materials Vol. 29 2015 (pages 224-236), ISSN 1473-2262
J. C. Strum, J. H. Johnson, J. Ward, H. Xie, J. Feild, A. Hester, A. Alford and K. M. Waters Mol Endocrinol. 2009; 23 (11): 1876-84.