ZenComplete™: Protein Secretion
A growing family of adipo-cytokines have been shown to play critical roles in the etiology of obesity and type II diabetes. ZenBio offers an adiponectin assay and a multiplexed assay to measure some of these important adipokines.
The development of non-insulin dependent (Type 2) diabetes may involve dysregulation of adiponectin secretion. Supporting the link between obesity and Type 2 diabetes, decreased adiponectin secretion correlates with insulin resistance. Additionally, adiponectin appears to be a potent insulin enhancer linking adipose tissue and whole body glucose metabolism. This assay measures adiponectin in either human serum or conditioned medium from the culture of human cells.
Figure 1 shows several analytes from cultured human preadipocytes, adipocytes, or adipocytes treated with Rosiglitazone. Data are expressed as pg/ml.
The following panel is available: IL-1., Il-6, IL-8, adiponectin, HGF, Leptin, MCP-1, PAI-1 (active), PAI-1 (total), Resistin, NGF and TNF.. Customers may almost any combination of adipokines. All analytes will be measured from the same well. The assay is done in duplicate in cultured human cells.
|CA-65||Human Adipocyte Adiponectin Secretion Assay||Assay||Call|
|CA-110||Human Adipocyte Multiplex Adipokine Secretion Assay||Assay||Call|
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