ZenBio offers cells, tissue, and serum from a diverse group of donor populations. Products are available from mixed donor lots, individual donor lots and a variety of disease states such as type II diabetes, hypertension, and others. Often, ZenBio is able to provide additional value added information such as blood panels and history of disease. In the event we do not have samples from a donor demographic that meets your needs, we are able to custom tailor a solution.
Please see the ZenBio white paper titled Comprehensive Procurement Program for an example of how we were able to meet the tissue and cultured cell needs of a top 10 pharmaceutical company. We work with an extensive network of US surgeons and procure all of our tissue from fully consented donors.
Below is a brief example of our other customized procurement and product programs.
One customer was interested in a comprehensive biomarker discovery effort and requested the following from living healthy donors undergoing elective surgery: 6 obese diabetic females (BMI greater than 35 and fasting blood glucose over 125) and 6 non obese, non-diabetic females (BMI under 28 and fasting blood glucose under 100). The following was for subcutaneous adipose tissue but we have performed similar services for customers requiring omental or mesenteric adipose or even as matched sets.
- 40 million cultured adipocytes
- 5 ml of serum
- 20 µg total RNA from cultured adipocytes
- 20 µg total RNA from adipose tissue (tissue had to be flash frozen in the surgery suite within 45 minutes after removal
- 1 gram flash frozen adipose tissue
- 1 gram Formalin fixed adipose tissue
- full deidentified patient chart information including: fasting blood glucose, age, height, weight, sex, current medications, patient and family history of disease.
Custom Culture Services
ZenBio offers an extensive array of cell types and plate formats in our regular catalog. When you require a cell type or plating format not currently listed, please let us know. We are able to work with our surgical partners to obtain various additional tissue types as well as isolate various cell types from tissue we currently receive.
One example of custom plating is switching the plate type to white plates with clear bottoms instead of the normal clear cell culture plates additionally we can accommodate special plating requests such as culturing cells on gelatin coated glass cover slips.
In addition to offering cells plated in nearly any format you require, we have custom plating and screening packages available. We are able to offer screening packages that include plated differentiated cells starting at 500 plates and running up to any number you require. Screening packages contain fully quality controlled cells at passage 4 and are cost effectively enable you to screen you compounds in a human cell system. ZenBio's pricing for our million point screening packages starts at under 25 cents per point.
To learn more about our services, please contact our Services Team